| 名稱 | ERBB2 p.L755S Reference Standard 標準品 |
| 型號 | CBP10270 |
| 報價 |  |
| 特點 | ERBB2 p.L755S Reference Standard |
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聯系人：蔣經理
電話：4008750250
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手機：18066071954
地址：南京市棲霞區緯地路9號
Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區緯地路9號
Email： zhangxiangwen@cobioer.com
產品展示 / PRODUCTS
- 詳細內容
CBP10270 | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) L755S lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). L755S results in increased phosphorylation of Erbb2 (Her2), activation of downstream signaling, is transforming in cell culture (PMID: 29967253), and is associated with resistance to Erbb2 (Her2)-targeted therapies (PMID: 22046346, PMID: 28487443). |
| Technical Data | |
| DNA Change | c.2264T>C |
| AA Change | p.L755S |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000269571 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr17:37880220 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
