| 名稱(chēng) | U2AF1 p.S34F Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10221 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | U2AF1 p.S34F Reference Standard |
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10221U2AF1 p.S34F Reference Standard 標(biāo)準(zhǔn)品
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CBP10221 | |
| Format | Genomic DNA |
| Description | U2AF1 S34F is a hotspot mutation (PMID: 28986033) that lies within the C3H1-type 1 Zinc finger region of the U2af1 protein (UniProt.org). S34F confers a gain of function to the U2af1 protein as indicated by aberrant splicing of U2af1 target genes in cell culture (PMID: 25267526, PMID: 28436936), ectopic expression, and promotion of cell proliferation in culture (PMID: 29991672). |
| Technical Data | |
| DNA Change | c.101C>T |
| AA Change | p.S34F |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 25% |
| Transcript | ENST00000291552 |
| Cosmic ID | COSM166866 |
| Chr position(GRCh37) | chr21:44524456 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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